14791-78-7

Basic information

• Product Name: 2-FLUORO-BENZENE-1,4-DIAMINE
• Synonyms: 2-FLUORO-BENZENE-1,4-DIAMINE
• CAS NO: 14791-78-7
• Molecular Formula: C₆H₇FN₂
• Molecular Weight: 126.13
• Mol File: 14791-78-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 87.5-89.0 °C
• Boiling Point: 256.1 °C at 760 mmHg
• Flash Point: 112.9 °C
• Appearance: /
• Density: 1.284 g/cm³
• Vapor Pressure: 0.0157mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.84±0.10(Predicted)
• CAS DataBase Reference: 2-FLUORO-BENZENE-1,4-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-BENZENE-1,4-DIAMINE(14791-78-7)
• EPA Substance Registry System: 2-FLUORO-BENZENE-1,4-DIAMINE(14791-78-7)

Safety Data

• Hazardous Substances Data: 14791-78-7(Hazardous Substances Data)

Usage

General Description

2-Fluoro-benzene-1,4-diamine, also known as 1,4-Diamino-2-fluorobenzene, is a chemical compound with the molecular formula C6H7F2N2. It is a fluorinated aromatic amine that is commonly used in the synthesis of various pharmaceuticals and organic compounds. 2-Fluoro-benzene-1,4-diamine is a building block for the production of fluorinated drugs and agrochemicals, and it also has potential applications in materials science and polymer chemistry. The compound's fluorinated structure and amino groups make it a versatile starting material for the creation of new compounds and can be used in organic chemistry research and pharmaceutical development. However, it is important to handle this compound with caution and adhere to proper safety protocols due to its potentially hazardous properties.

InChI:InChI=1/C6H7FN2/c7-5-3-4(8)1-2-6(5)9/h1-3H,8-9H2

Upstream product

• 2369-13-3 3-fluoro-4-nitroaniline 
• 57946-56-2 2-fluoro-4-chloroaniline 
• 105931-73-5 1-bromo-3-fluoro-4-iodobenzene 

Downstream Products

• 7442-07-1 6-amino-2-mercaptobenzothiazole 

Relevant articles and documents

Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides

The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.

A 4, 4 - dimethoxy - 2, 2 - bipyridyl silver catalytic hydrogenation of aromatic nitro compound synthesis of aromatic amines (by machine translation)

The invention discloses a 4, 4 - dimethoxy - 2, 2 - bipyridyl silver catalytic hydrogenation of aromatic nitro compound synthesis of aromatic amines, the method uses a cheap, easy synthesis of 4, 4 - dimethoxy - 2, 2 - bipyridyl silver as catalyst, in order to green, environmental protection, non-toxic as the hydrogen source, the aromatic nitro compound in the relatively mild reaction conditions, one-step reaction can synthesize aromatic amine. The invention has simple operation, catalyst is cheap and easy and small consumption, mild reaction conditions, to substrate demonstrates better functional group tolerant, high product yield, industrial manufacturing cost, it has very good application prospect. (by machine translation)

Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts

A method for the Pd-catalyzed arylation of ammonia with a wide range of aryl and heteroaryl halides, including challenging five-membered heterocyclic substrates, is described. Excellent selectivity for monoarylation of ammonia to primary arylamines was achieved under mild conditions or at rt by the use of bulky biarylphosphine ligands (L6, L7, and L4) as well as their corresponding aminobiphenyl palladacycle precatalysts (3a, 3b, and 3c). As this process requires neither the use of a glovebox nor high pressures of ammonia, it should be widely applicable.