147959-19-1

Basic information

• Product Name: (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE
• Synonyms: (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE;tert-butyl (4S)-2,2-diMethyl-4-(2-oxoethyl)-1,3-oxazolidine-3-carboxylate;Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate;(4S)-2,2-Dimethyl-4-(2-Oxoethyl)-3-Oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester;(4S)-2,2-dimethyl-4-(2-oxoethyl)-oxazolidine-3-carboxylic acid tert-butyl ester;3-tert-butoxycarbonylamino-2,3-dideoxy-3,4-N,O-isopropylidene-aldehydo-D-glycero-tetrose
• CAS NO: 147959-19-1
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.3
• Mol File: 147959-19-1.mol
• Article Data: 14

Chemical Properties

• Melting Point: <40 °C
• Boiling Point: 324.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.051±0.06 g/cm3(Predicted)
• PKA: -2.22±0.60(Predicted)
• CAS DataBase Reference: (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE(147959-19-1)
• EPA Substance Registry System: (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE(147959-19-1)

Safety Data

• Hazardous Substances Data: 147959-19-1(Hazardous Substances Data)

Usage

General Description

(S)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate is a chemical compound that belongs to the class of oxazolidine carboxylates. It is a stable and versatile molecule that is commonly used for various applications in organic synthesis. (S)-TERT-BUTYL 2,2-DIMETHYL-4-(2-OXOETHYL)OXAZOLIDINE-3-CARBOXYLATE is known for its ability to act as a chiral building block, making it useful in the synthesis of complex organic molecules and pharmaceutical products. It is also used in the production of agrochemicals, dyes, and other specialty chemicals. Additionally, this compound has potential applications in the field of materials science, including as a precursor for the synthesis of polymers and advanced materials. Overall, (S)-Tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate is a valuable compound with a wide range of potential uses across various industries.

Upstream product

• 79-37-8 oxalyl dichloride 
• 147959-18-0 (4S)-2,2-dimethyl-4-(2-hydroxyethyl)oxazolidine-3-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 205491-14-1 methyl [(4S)-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidin-4-yl]ethanoate 
• 1062238-49-6 methyl (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoate 
• 59768-74-0 (S)-2-t-butoxycarbonylaminosuccinic acid 4-methyl ester 
• 133625-87-3 tert-butyl (4S)-2,2-dimethyl-4-vinyl-1,3-oxazolidine-3-carboxylate 
• 128427-09-8 (S)-N-tert-butoxycarbonyl-aspartic acid diethyl ester 
• 850996-87-1 (4S)-4-[2-(1-methoxy-1-methylethoxy)ethyl]-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 128427-10-1 (S)-2-(tert-butoxycarbonylamino)-1,4-butanediol 
• 130622-08-1 dimethyl N-tert-butoxycarbonyl-L-aspartate 

Downstream Products

• 1166394-91-7 (S)-tert-butyl 4-(4-hydroxybutyl)-2,2-dimethyloxazolidine-3-carboxylate 

Relevant articles and documents

Synthesis of sphingosine analogues: Stereoselective synthesis of 3- deoxysphingosine and cis-isomers

Both enantiomers of 3-deoxysphingosine as well as their cis-isomers were synthesized stereoselectively from L- and D-serine.

NOVEL QUINOLINE-SUBSTITUTED COMPOUND

An object to be achieved by the present invention is to provide a novel compound having EGFR inhibitory effects and cell growth inhibitory effects, as well as a medication useful for the prevention and/or treatment of cancer based on the EGFR inhibitory effects. The present invention provides a compound represented by Formula (I) below, or a salt thereof.

FACTOR XIa INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.