148-78-7 Usage
General Description
The chemical 4-[[4-[Bis(2-chloroethyl)amino]phenoxy]carbonylamino]benzoic acid, also known as bendamustine, is a nitrogen mustard alkylating agent with both chemotherapeutic and immunosuppressive activities. It is used primarily in the treatment of chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). Bendamustine exerts its antitumor effects by alkylating and crosslinking DNA, leading to inhibition of DNA replication and RNA transcription and eventual cell death. Additionally, it has been shown to induce immunogenic cell death, which can enhance the immune response against cancer cells. The chemical has demonstrated significant efficacy and tolerance in the treatment of various hematological malignancies and is an important option in the management of these diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 148-78-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 148-78:
(5*1)+(4*4)+(3*8)+(2*7)+(1*8)=67
67 % 10 = 7
So 148-78-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H18Cl2N2O4/c19-9-11-22(12-10-20)15-5-7-16(8-6-15)26-18(25)21-14-3-1-13(2-4-14)17(23)24/h1-8H,9-12H2,(H,21,25)(H,23,24)
