148214-62-4

Basic information

• Product Name: 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI)
• Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI);2-Methoxy-7H-Pyrrolo[2,3-d]pyrimidine;2-Methoxy-1H-pyrrolo[2,3-d]pyrimidine
• CAS NO: 148214-62-4
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.14998
• Product Categories: PYRIMIDINE
• Mol File: 148214-62-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.328 g/cm³
• Refractive Index: 1.658
• CAS DataBase Reference: 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI)(148214-62-4)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI)(148214-62-4)

Safety Data

• Hazardous Substances Data: 148214-62-4(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI) is a chemical compound with the molecular formula C9H8N2O. It is a heterocyclic organic compound that contains a pyrrolopyrimidine ring with a methoxy group attached to the second carbon atom. 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI) is an important intermediate in the synthesis of various pharmaceuticals and biologically active compounds. It has potential applications in the field of medicinal chemistry and drug development. The methoxy group in the structure can play a crucial role in modulating the compound's physicochemical properties and pharmacological activities. Overall, 1H-Pyrrolo[2,3-d]pyrimidine, 2-methoxy- (9CI) is a versatile and valuable chemical compound with a broad range of potential applications in the pharmaceutical industry.

InChI:InChI=1/C7H7N3O/c1-11-7-9-4-5-2-3-8-6(5)10-7/h2-4H,1H3,(H,8,9,10)

Upstream product

• 90057-08-2 4-Chlor-2-methoxy-7H-pyrrolo<2,3-d>pyrimidin 
• 148214-60-2 (Z)-4-acetylamino-5-(2-ethoxyethenyl)-2-methoxypyrimidine 
• 3289-47-2 4-amino-2-methoxypyrimidine 
• 148214-55-5 4-acetylamino-2-methoxypyrimidine 
• 148214-53-3 4-acetylamino-5-bromo-2-methoxypyrimidine 
• 124-41-4 sodium methylate 
• 335654-06-3 2-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 67-56-1 methanol 
• 1378761-82-0 2-methoxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 1060815-93-1 C₇H₆IN₃O 
• 937162-93-1 3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-3H-2-one 
• 322728-22-3 pyrrolo[2,3-d]pyrimidin-3H-2-one 
• 155532-17-5 7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 

Relevant articles and documents

Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents

Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin

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Synthesis of 2'-deoxyisoinosine and related 2'-deoxyribonucleosides

Various 2-substituted purine and pyrrolo[2,3-d]pyrimidine 2'-deoxyribonucleosides with methylthio (13a), chloro (13b), methoxy (9b), and oxo (2, 3) substituents at C(2) are prepared. They are obtained either via stereoselective nucleobase-anion glycosylation or by base transformation. A three-step synthesis of the unknown 2'-deoxyisoinosine (2) from 2'-deoxyguanosine (15) is described. Compound 2 as well as its 7-deazapurine derivative 3 exhibit strong fluorescence.