148217-23-6Relevant articles and documents
Synthesis and Phosphodiesterase Activity of Carboxylic Acid Mimetics of Cyclic Guanosine 3',5'-Monophosphate
Tulshian, Deen,Czarniecki, Michael,Doll, Ronald J.,Ahn, Ho-Sam
, p. 1210 - 1220 (2007/10/02)
Synthetic analogs of the natural product griseolic acid in which a guanine base is substituted for the adenine have been prepared.The best of these compounds inhibits a cyclic guanosine 3',5'-monophosphate (cGMP) phosphodiesterase preparation with an IC50