148259-10-3Relevant academic research and scientific papers
Transition-metal-free persulfuration to construct unsymmetrical disulfides and mechanistic study of the sulfur redox process
Xiao, Xiao,Feng, Minghao,Jiang, Xuefeng
, p. 4208 - 4211 (2015)
A sulfur redox process has been developed between sulfinate and thiosulfate, which efficiently affords diverse unsymmetrical disulfides and provides a new method to modify pharmaceuticals and natural products without requiring an extra oxidant or reductant. Gram-scale investigation further demonstrates the practicality and application potential of this process. Isolated key intermediates and a series of control experiments afford an unusual process, which reveals the mechanism of comproportionation and the transition-metal-free sulfur redox process.
Synthesis and biochemical studies of estrone sulfatase inhibitors
Li, Pui-Kai,Pillai, Radhakrishnan,Young, Barry L.,Bender, William H.,Martino, Dino M.,Lin, Fu-Tyan
, p. 106 - 111 (2007/10/02)
The synthesis and biochemical evaluation of estrone sulfatase inhibitors are described. Inhibitors were designed through modifications of the substrate estrone sulfate. An in vitro assay using the microsomal fraction isolated from human term placenta was
