1483-55-2

Basic information

• Product Name: 2-Bromo-5-(trifluoromethyl)benzonitrile
• Synonyms: 2-BROMO-5-(TRIFLUOROMETHYL)BENZONITRILE;2-Bromo-5-(trifluoromethyl)benzonitrile 98%;2-Bromo-5-(trifluoromethyl)benzonitrile98%;2-Bromo-2-(trifluoromethyl)benzonitrile;4-Bromo-3-cyanobenzotrifluoride;2-BroMo-5-(trifluoroMethyl)benzonitrile, 97+%;Benzonitrile, 2-bromo-5-(trifluoromethyl)-
• CAS NO: 1483-55-2
• Molecular Formula: C₈H₃BrF₃N
• Molecular Weight: 250.02
• Product Categories: Nitrile;Fluorine series
• Mol File: 1483-55-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 50-51°C
• Boiling Point: 107-115°C (10 torr)
• Flash Point: 116.7 °C
• Appearance: White solid
• Density: 1.71 g/cm³
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 2-Bromo-5-(trifluoromethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-(trifluoromethyl)benzonitrile(1483-55-2)
• EPA Substance Registry System: 2-Bromo-5-(trifluoromethyl)benzonitrile(1483-55-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 26-36/37/39
• RIDADR: 3439
• HazardClass: IRRITANT
• Hazardous Substances Data: 1483-55-2(Hazardous Substances Data)

Usage

Chemical Properties

White crystals

Upstream product

• 454-79-5 2-Bromo-5-trifluoromethylaniline 
• 143-33-9 sodium cyanide 

Downstream Products

• 102684-91-3 2-bromo-5-(trifluoromethyl)benzaldehyde 
• 1234790-74-9 2-{3-[2-(2,3-difluoro-phenyl)-imidazo[4,5-d]pyridazin-5-ylmethyl]-isoxazol-5-yl}-5-trifluoromethyl-benzonitrile 
• 1234790-96-5 C₁₇H₁₅F₃N₂O₃ 
• 1234790-91-0 C₁₃H₉F₃N₂O₄S 
• 1234790-97-6 C₁₂H₇F₃N₂O₂ 
• 1234790-90-9 2-ethynyl-5-trifluoromethyl-benzonitrile 
• 1450923-87-1 6-chloro-4-(2-cyano-4-(trifluoromethyl)phenyl)-N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide 
• 1450920-03-2 4-(2-cyano-4-(trifluoromethyl)phenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide 
• 944836-22-0 (S)-2-(2-(bis(4-trifluoromethyl-phenyl)-phosphino))-5-(4-trifluoromethyl-phenyl)-4-tert-butyl-4,5-dihydro-oxazole 
• 944836-38-8 (S)-2-(2-bromo-5-(trifluoromethyl)phenyl)-4-(tert-butyl)-4,5-dihydrooxazole 

Relevant articles and documents

Process for producing trifluoromethylbenzylamines

The invention relates to a process for producing a trifluotomethylbenzylamine represented by the following general formula (1), 1where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4. The process includes hydrogenating a trifluoromethylbenzonitrile by hydrogen in an organic solvent in the presence of ammonia and a catalyst containing a platinum group element. This trifluoromethylbenzonitrile is represented by the following general formula (2), 2where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine at an extremely high yield.

3-Aminoindazole derivatives

.Iadd.Pharmaceutical compositions having muscle relaxant and analgesic activity containing 3-aminoindazoles..Iaddend.

A TRIFLUOROMETHYL BENZODIAZEPINE DERIVATIVE.

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