148312-62-3Relevant articles and documents
Substituted cyclopropylamino-1,3,5-triazines
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, (2008/06/13)
New substituted cyclopropylamino-1,3,5-triazines having the formula STR1 wherein R1 is C1 -C3 -alkyl, C3 -C5 -cycloalkyl or C1 -C3 -alkyl-C3 -C5 -cycloalkyl R2 is bis(2-hydroxyethyl)amino, 3-hydroxy-1-azetidinyl, 3-methoxy-1-azetidinyl, 3-oxo-1-azetidinyl, morpholino, 4-hydroxypiperidino, thiomorpholino, thiomorpholino S-oxide, thiomorpholino S,S-dioxide, 3-thiazolidinyl, 3-thiazolidinyl S-oxide, 3-thiazolidinyl S,S-dioxide or 8-oxa-3-azabicyclo[3,2,1]oct-3-yl. Processes for the preparation thereof and pharmaceutical composition containing them are also given. The compounds are useful for the treatment of disorders associated with Alzheimer's disease, senile dementia, Alzheimer's type and with any evolutive cognitive pathology, and also for the treatment of depression, anxiety, mood disturbances, inflammatory phenomena and asthma.