148437-41-6 Usage
General Description
1,2-dihexanoyl-sn-glycero-3-phosphoinositol, also known as DHPI, is a synthetic derivative of inositol phospholipids. It is a phosphatidylinositol (PI) analog with two hexanoyl chains attached to the sn-1 and sn-2 positions of the glycerol backbone. DHPI is commonly used as a chemical tool to study the role of PI signaling in cellular processes. It has been shown to inhibit the enzymatic activity of PI 3-kinase, a key regulator of cell growth, proliferation, and survival. Additionally, DHPI has been used to investigate the role of PI lipids in membrane trafficking, cell migration, and cytoskeletal dynamics. Overall, DHPI is a valuable tool for studying the functions of PI lipids and their associated signaling pathways in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 148437-41-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,4,3 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 148437-41:
(8*1)+(7*4)+(6*8)+(5*4)+(4*3)+(3*7)+(2*4)+(1*1)=146
146 % 10 = 6
So 148437-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H39O13P/c1-3-5-7-9-14(22)31-11-13(33-15(23)10-8-6-4-2)12-32-35(29,30)34-21-19(27)17(25)16(24)18(26)20(21)28/h13,16-21,24-28H,3-12H2,1-2H3,(H,29,30)/t13-,16?,17-,18+,19+,20+,21?/m1/s1
148437-41-6Relevant articles and documents
Synthesis of Short Chain Phosphatidylinositols
Garigapati, Venkata R.,Roberts, Mary F.
, p. 769 - 772 (1993)
A short, convenient, and versatile synthesis of short chain D- and L-phosphatidylinositols is reported.