148587-50-2Relevant academic research and scientific papers
Synthesis of (2S,4S)-2-Carboxy-4-Pyrrolidine Acetic Acid, a Conformationally Constrained 2-Amino Adipic Acid Analogue
Langlois, Nicole,Rojas, Anne
, p. 2477 - 2480 (2007/10/02)
(2S,4S)-2-carboxy-4-pyrrolidine acetic acid was synthesized from (S)-pyroglutamic acid in 26 percent overall yield by a regiospecific deprotonation of the N-methoxycarbonyl benzylester 4. Key Words: pyroglutamic acid, excitatory amino-acids, alkyl bromoacetate, sodium cyanoborohydride.
