148615-76-3Relevant academic research and scientific papers
SYNTHESIS OF AN ADVANCED FORSKOLIN INTERMEDIATE
Bick, Stefan,Zimmermann, Silke,Meuer, Heike,Sheldrick, William S.,Welzel, Peter
, p. 2457 - 2468 (1993)
The 8,13-epoxylabdane derivative rac-19 was prepared in eight steps commencing from (E,E)-farnesol (8).Key reactions are the formation of 7 from drimenal (9b) and 6, Sharpless I epoxidation (7->11), epoxy alcohol oxidation (11->16), reductive epoxide cleavage (16->15), peracid epoxidation (15->18), and the trimethylsilyl triflate-mediated conversion of 18 into 19.
