14866-28-5

Basic information

• Product Name: 1-(2,4-dichlorophenyl)ethane-1,2-diol
• Synonyms: 1-(2,4-Dichlorophenyl)-1,2-ethanediol;1-(2,4-dichlorophenyl)ethane-1,2-diol
• CAS NO: 14866-28-5
• Molecular Formula: C₈H₈Cl₂O₂
• Molecular Weight: 207.05392
• EINECS: 238-935-3
• Mol File: 14866-28-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 358.5°C at 760 mmHg
• Flash Point: 170.6°C
• Appearance: /
• Density: 1.458g/cm³
• Vapor Pressure: 9.18E-06mmHg at 25°C
• Refractive Index: 1.601
• PKA: 12.85±0.20(Predicted)
• CAS DataBase Reference: 1-(2,4-dichlorophenyl)ethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dichlorophenyl)ethane-1,2-diol(14866-28-5)
• EPA Substance Registry System: 1-(2,4-dichlorophenyl)ethane-1,2-diol(14866-28-5)

Safety Data

• Hazardous Substances Data: 14866-28-5(Hazardous Substances Data)

Usage

Uses

1-(2,4-Dichlorophenyl)-1,2-ethanediol (Isoconazole Impurity 7) is an impurity of Isoconazole (I798250), an antibacterial and antifungal agent used to treat vaginitis.

InChI:InChI=1/C8H8Cl2O2/c9-5-1-2-6(7(10)3-5)8(12)4-11/h1-3,8,11-12H,4H2

Downstream Products

• 59363-73-4 1-[4-(2,4-dichloro-phenyl)-2-phenyl-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59363-69-8 1-[4-(2,4-dichloro-phenyl)-2-p-tolyl-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59364-97-5 1-[2-(3-chloro-phenyl)-4-(2,4-dichloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59363-23-4 1-[2-(4-chloro-phenyl)-4-(2,4-dichloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59401-19-3 1-[2-(4-bromo-phenyl)-4-(2,4-dichloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59364-63-5 1-[2-(2-chloro-phenyl)-4-(2,4-dichloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59363-89-2 1-[2,4-bis-(2,4-dichloro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59362-68-4 (cis+trans)-2-(bromomethyl)-2-(4-bromophenyl)-4-(2,4-dichlorophenyl)-1,3-dioxolane 
• 59362-66-2 2-(bromomethyl)-2-(p-chlorophenyl)-4-(2,4-dichlorophenyl)-1,3-dioxolane 
• 59365-57-0 2-Bromomethyl-2-(2-chloro-phenyl)-4-(2,4-dichloro-phenyl)-[1,3]dioxolane 
• 59362-71-9 2-Bromomethyl-4-(2,4-dichloro-phenyl)-2-p-tolyl-[1,3]dioxolane 
• 59365-52-5 2-Bromomethyl-4-(2,4-dichloro-phenyl)-2-phenyl-[1,3]dioxolane 
• 59365-19-4 2-Bromomethyl-2,4-bis-(2,4-dichloro-phenyl)-[1,3]dioxolane 

Relevant articles and documents

Ru-MACHO-Catalyzed Highly Chemoselective Hydrogenation of α-Keto Esters to 1,2-Diols or α-Hydroxy Esters

A ruthenium pincer catalyst has been shown to be highly effective for the hydrogenation of a wide range of α-keto esters, affording either diols or hydroxy esters depending on the choice of reaction conditions. Strong base, high temperature, and pressure favor the formation of diols whilst the opposite is true for the hydroxy esters.