148672-75-7

Basic information

• Product Name: 1-Azabicyclo[3.2.1]octane-5-Methanol
• Synonyms: 1-Azabicyclo[3.2.1]octane-5-Methanol
• CAS NO: 148672-75-7
• Molecular Formula: C₈H₁₅NO
• Molecular Weight: 141.2108
• Mol File: 148672-75-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Azabicyclo[3.2.1]octane-5-Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azabicyclo[3.2.1]octane-5-Methanol(148672-75-7)
• EPA Substance Registry System: 1-Azabicyclo[3.2.1]octane-5-Methanol(148672-75-7)

Safety Data

• Hazardous Substances Data: 148672-75-7(Hazardous Substances Data)

Upstream product

• 119102-52-2 ethyl 1-azabicyclo[3.2.1]octane-5-carboxylate 

Downstream Products

• 141593-56-8 (+/-) 1-Azabicyclo[3.2.1]oct-5-ylcarboxaldehyde 
• 148672-90-6 4-Amino-5-chloro-2-methoxybenzoic acid 1-azabicyclo[3.2.1]oct-5-ylmethyl ester 

Relevant articles and documents

AZA-BRIDGED-RING COMPOUND

[PROBLEMS] Provided is a compound which has an antagonistic action on a muscarinic M3 receptor and is useful as an active ingredient of a prophylactic and/or therapeutic agent for an inflammatory disease such as a chronic obstructive pulmonary disease (COPD), asthma and the like. [MEANS FOR SOLVING PROBLEMS] The present inventors have made studies on a compound having an antagonistic action on the binding of a muscarinic M3 receptor, and they have found that an aza-bridged-ring compound or a salt thereof has an antagonistic action on the binding of a muscarinic M3 receptor, thereby completing the present invention. The aza-bridged-ring compound of the present invention has an antagonistic action on the binding of a muscarinic M3 receptor, and can be used as a prophylactic and/or therapeutic agent for an inflammatory disease such as a chronic obstructive pulmonary disease (COPD), asthma and the like.

Pleuromutilin derivatives as antimicrobials

The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy.