148679-63-4

Upstream product

• 2014-75-7 2-(phenylthio)ethanamine 
• 41010-04-2 4-nitro-2-(2-(phenylthio)ethyl)isoindoline-1,3-dione 

Downstream Products

• 205596-38-9 N-[1-(3,4-Dimethoxy-phenyl)-ethyl]-N-(2-phenylsulfanyl-ethyl)-formamide 
• 205596-44-7 N-(2-Benzenesulfinyl-ethyl)-N-[1-(3,4-dimethoxy-phenyl)-ethyl]-formamide 
• 205596-53-8 6,7-Dimethoxy-1-methyl-4-phenylsulfanyl-3,4-dihydro-1H-isoquinoline-2-carbaldehyde 
• 490-53-9 (+/-)-carnegine 
• 148679-65-6 (2-Benzenesulfinyl-ethyl)-[1-(3,4-dimethoxy-phenyl)-ethyl]-carbamic acid methyl ester 

Relevant academic research and scientific papers

A highly efficient synthesis of 1-methyl-, 1-benzyl-, and 1-phenyl-1,2,3,4-tetrahydroisoquinolines by a modified pummerer reaction

(±)-1-Methyl- (13b), (±)-1-benzyl- (13c), and (±)-1-phenyl- (13d)-1,2,3,4-tetrahydroisoquinolines, which are supposed to participate in the pathogenesis of Parkinson's disease, were prepared by using a modified Pummerer reaction as a key step in excellent overall yields from the commercially available ketones (4b-c).

A FACILE ROUTE TO TETRAHYDROISOQUINOLINE ALKALOIDS VIA SULFOXIDE MEDIATED CYCLIZATION

A facile route to 1,2,3,4-tetrahydroisoquinoline framework has been developed by employing the sulfoxide mediated cyclization reaction.Utilizing the reaction developed some naturally occurring isoquinoline alkaloids have been synthesized.