148706-06-3

Basic information

• Product Name: (+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL
• Synonyms: HNE-D3;(E)-4-HYDROXYNONENAL-D3;4-HNE-D3;(+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL;4-HYDROXY NONENAL-D3;(E)-9,9,9-trideuterio-4-hydroxynon-2-enal
• CAS NO: 148706-06-3
• Molecular Formula: C9H13D3O2
• Molecular Weight: 159.24
• Mol File: 148706-06-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL(148706-06-3)
• EPA Substance Registry System: (+/-)-4-HYDROXY-9,9,9,NON-2E-ENAL(148706-06-3)

Safety Data

• Hazardous Substances Data: 148706-06-3(Hazardous Substances Data)

Usage

Uses

4-hydroxy Nonenal-d3 (4-HNF-d3) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE by GC- or LC-mass spectrometry. 4-HNE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid. 4-HNE is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-HNE inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 μM.