Squalamine is a steroid and aminosterol compound found in the tissues of certain shark species and in small amounts in other marine organisms. It possesses antibacterial, antifungal, and antiviral properties, working by disrupting the cell membrane of pathogens, making it difficult for them to survive and replicate. Squalamine also has potential as a treatment for various medical conditions due to its ability to inhibit angiogenesis and reduce inflammation. Furthermore, it has been found to regulate cholesterol and lipid metabolism, which could be valuable in the development of new treatments for cardiovascular diseases.
148717-90-2
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Basic information
- Product Name: squalamine
- Synonyms: MSI 1256;(3β，5α，7α)-3-[[3-((4-Aminobutyl)amino)propyl]amino]cholestane-7，24-diol-24-hydrogen sulfate
- CAS NO:148717-90-2
- Molecular Formula: C34H65N3O5S
- Molecular Weight: 627.969
- EINECS: N/A
- Product Categories: N/A
- Mol File: 148717-90-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: 1.13g/cm3
- Refractive Index: 1.548
- Storage Temp.: N/A
- Solubility: N/A
- PKA: -3.49±0.18(Predicted)
- CAS DataBase Reference: squalamine(CAS DataBase Reference)
- NIST Chemistry Reference: squalamine(148717-90-2)
- EPA Substance Registry System: squalamine(148717-90-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 148717-90-2(Hazardous Substances Data)
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148717-90-2 Usage
Uses
Used in Pharmaceutical Industry:Squalamine is used as an antimicrobial agent for its ability to disrupt the cell membrane of pathogens, making it difficult for them to survive and replicate.
Used in Cancer Treatment:
Squalamine is used as a potential treatment for various medical conditions, including cancer, due to its ability to inhibit angiogenesis and reduce inflammation.
Used in Ophthalmology:
Squalamine is used as a potential treatment for eye diseases, leveraging its anti-inflammatory properties and potential to inhibit angiogenesis.
Used in Neurology:
Squalamine is used as a potential treatment for certain neurological disorders, due to its anti-inflammatory and other therapeutic properties.
Used in Cardiovascular Disease Treatment:
Squalamine is used as a potential treatment for cardiovascular diseases, given its ability to regulate cholesterol and lipid metabolism.
Used in Drug Development:
Squalamine is used as a compound in the development of new treatments, owing to its multifaceted therapeutic potential across various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 148717-90-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,7,1 and 7 respectively; the second part has 2 digits, 9 and 0 respectively.Calculate Digit Verification of CAS Registry Number 148717-90:
(8*1)+(7*4)+(6*8)+(5*7)+(4*1)+(3*7)+(2*9)+(1*0)=162
162 % 10 = 2
So 148717-90-2 is a valid CAS Registry Number.
InChI:InChI=1/C34H65N3O5S/c1-23(2)31(42-43(39,40)41)12-9-24(3)27-10-11-28-32-29(14-16-34(27,28)5)33(4)15-13-26(21-25(33)22-30(32)38)37-20-8-19-36-18-7-6-17-35/h23-32,36-38H,6-22,35H2,1-5H3,(H,39,40,41)/t24-,25-,26+,27-,28+,29+,30-,31-,32+,33+,34-/m1/s1
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