148717-90-2

Basic information

• Product Name: squalamine
• Synonyms: MSI 1256;(3β，5α，7α)-3-[[3-((4-Aminobutyl)amino)propyl]amino]cholestane-7，24-diol-24-hydrogen sulfate
• CAS NO: 148717-90-2
• Molecular Formula: C34H65N3O5S
• Molecular Weight: 627.969
• Mol File: 148717-90-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.13g/cm³
• Refractive Index: 1.548
• PKA: -3.49±0.18(Predicted)
• CAS DataBase Reference: squalamine(CAS DataBase Reference)
• NIST Chemistry Reference: squalamine(148717-90-2)
• EPA Substance Registry System: squalamine(148717-90-2)

Safety Data

• Hazardous Substances Data: 148717-90-2(Hazardous Substances Data)

Usage

General Description

Squalamine is a chemical compound found in the tissues of certain shark species, as well as in small amounts in some other marine organisms. It is a steroid and aminosterol that has been shown to have antibacterial, antifungal, and antiviral properties. Squalamine works by disrupting the cell membrane of pathogens, making it difficult for them to survive and replicate. Research has also suggested that squalamine may have potential as a treatment for various medical conditions, including cancer, eye diseases, and certain neurological disorders, due to its ability to inhibit angiogenesis and reduce inflammation. Additionally, squalamine has been found to have an ability to regulate cholesterol and lipid metabolism, which could be valuable in the development of new treatments for cardiovascular diseases.

InChI:InChI=1/C34H65N3O5S/c1-23(2)31(42-43(39,40)41)12-9-24(3)27-10-11-28-32-29(14-16-34(27,28)5)33(4)15-13-26(21-25(33)22-30(32)38)37-20-8-19-36-18-7-6-17-35/h23-32,36-38H,6-22,35H2,1-5H3,(H,39,40,41)/t24-,25-,26+,27-,28+,29+,30-,31-,32+,33+,34-/m1/s1