148761-44-8

Basic information

• Product Name: 4H-Furo[3,2-b]indole-2-carboxylic acid, 3-hydroxy-4-methyl-, methyl ester
• Synonyms: 4H-Furo[3,2-b]indole-2-carboxylic acid, 3-hydroxy-4-methyl-, methyl ester
• CAS NO: 148761-44-8
• Molecular Formula: C13H11NO4
• Molecular Weight: 245.23
• Mol File: 148761-44-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 323.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.41±0.1 g/cm3(Predicted)
• PKA: 9.52±0.30(Predicted)
• CAS DataBase Reference: 4H-Furo[3,2-b]indole-2-carboxylic acid, 3-hydroxy-4-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Furo[3,2-b]indole-2-carboxylic acid, 3-hydroxy-4-methyl-, methyl ester(148761-44-8)
• EPA Substance Registry System: 4H-Furo[3,2-b]indole-2-carboxylic acid, 3-hydroxy-4-methyl-, methyl ester(148761-44-8)

Safety Data

• Hazardous Substances Data: 148761-44-8(Hazardous Substances Data)

Upstream product

• 148761-43-7 methyl <(2-methoxycarbonyl)-N-methylindol-3-yloxy>acetate 
• 21716-68-7 methyl N-methylglycinate 
• 56434-56-1 methyl 3-hydroxy-1-methyl-1H-indole-2-carboxylate 

Relevant articles and documents

APPLICATION OF MAGNESIUM ALKOXIDES TO SYNTHESES OF BENZOHETEROCYCLIC COMPOUNDS

The Dieckmann condensations of methyl -X-acetates Ia-Ih (X = O, S, SO2, NH, NCH3) initiated by action of magnesium methoxide, ethoxide, isopropoxide and other basic reagents have been studied under various conditions.Whereas magnesium methoxide has comparable efficiency as sodium methoxide and potassium tert-butoxide in syntheses of benzoheterocyclic compounds IIa-IIh, magnesium ethoxide gives the ethyl ester IIb in a medium yield, and magnesium isopropoxide is quite inefficient in the condensation reaction.The alkylation of the esters IIa, IId, and IIg with methyl chloroaetate in the presence of sodium hydride in dimethylformamide gives the diesters IIi-IIk which on action by potassium tert-butoxide undergo the cyclization reaction to give esters III.