148773-73-3Relevant academic research and scientific papers
A straightforward synthesis of enantiomerically pure trans-2,5-bis(alkyloxymethyl) pyrrolidines by 1,3-dipolar cycloaddition reactions of azomethine ylides
Wittland, Claudia,Risch, Nikolaus
, p. 311 - 315 (2007/10/03)
A new efficient method for the stereoselective preparation of trans-2,5-bis(alkyloxymethyl)pyrrolidines (7) using easily available starting materials is described. The main step of this synthesis is the stereoselective formation of the pyrrolidine ring by
A convenient synthesis of enantiomeric pairs of 2,5-disubstituted pyrrolidines of C2-symmetry
Yamamoto,Hoshino,Fujimoto,Ohmoto,Sawada
, p. 298 - 302 (2007/10/02)
By the use of (-)-1-phenylethylamine as a chiral auxiliary, three diastereomeric isomers of 2,5-bis(methoxycarbonyl)pyrrolidine derivatives are prepared from dimethyl rac-2,5-dibromadipate and separted by crystallization and chromatographic fractionation
