148826-19-1Relevant articles and documents
A facile chemoenzymatic route to optically active 4,5-disubstituted-2E-hexenoate derivatives. I
Akita,Umezawa,Takano,Ohyama,Matsukura,Oishi
, p. 55 - 63 (2007/10/02)
The reaction of (±) methyl 4,5-trans-epoxy-2E-hexenoate (2) with aromatic nucleophiles having an electron-donating group in the presence of BF3 · Et2O gave the 4,5-anti-5-hydroxy-4- or/and 2,5-anti-5-hydroxy-2-substituted products. T
A facile chemoenzymatic route to enantiomerically pure 4,5-disubstituted-2-hexenoae derivatives
Akita,Umezawa,Takano,Matsukura,Oishi
, p. 3094 - 3096 (2007/10/02)
The reaction of 4,5-epoxy-2-hexenoate 2 and various nucleophiles in the presence of BF3.Et2O predominantly gave the (4,5)-5-hydroxy-4-substituted compounds. Among them, (±)-(4,5)-anti-5-hydroxy-4-thiophenoxy ester 17 was enantioselec