1488304-76-2Relevant academic research and scientific papers
Polyfunctional pyrazoles. 8*. Synthesis of 6-alkyl-2-aryl-2H- pyrazolo[4,3-d]pyrimidine-5,7(4H,6H)-diones based on ethyl 1-aryl-4- isocyanatopyrazole-3-carboxylates
Bratenko,Barus,Vovk
, p. 1345 - 1351 (2014/01/17)
A method for the preparation of 6-alkyl-2-aryl-2H-pyrazolo[4,3-d] pyrimidine-5,7(4H,6H)-diones in reaction of ethyl 1-aryl-4-isocyanatopyrazole-3- carboxylates with aliphatic amines followed by cyclization of the obtained 4-ureidopyrazole-3-carboxylic acid esters in the presence of bases is proposed.
