1488919-78-3

Basic information

• Product Name: 6-(1H-indol-3-yl)-3-methyl-4-(p-tolyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
• Synonyms: 6-(1H-indol-3-yl)-3-methyl-4-(p-tolyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
• CAS NO: 1488919-78-3
• Molecular Weight: 365.437
• Mol File: 1488919-78-3.mol

Chemical Properties

• CAS DataBase Reference: 6-(1H-indol-3-yl)-3-methyl-4-(p-tolyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(1H-indol-3-yl)-3-methyl-4-(p-tolyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile(1488919-78-3)
• EPA Substance Registry System: 6-(1H-indol-3-yl)-3-methyl-4-(p-tolyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile(1488919-78-3)

Safety Data

• Hazardous Substances Data: 1488919-78-3(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 20356-45-0 3-(1H-indol-3-yl)-3-oxo-propionitrile 
• 31230-17-8 3-amino-5-methylpyrazole 

Relevant articles and documents

Regioselective synthesis and antibacterial evaluation of a new class of substituted pyrazolo[3,4-b]pyridines

New derivatives of polyfunctional pyrazolo[3,4-b]pyridines were synthesised via a regioselective one-pot three-component reaction of 3- (cyanoacetyl)indole, 5-amino-3-methylpyrazole and arylaldehydes in excellent yields using Fe3+-montmorillonite as a reusable catalyst under conventional conditions and ultrasonic irradiation. In particular, valuable features of this method include high reaction rate, employment of a reusable catalyst, straightforward procedure, the easy work-up of the products and mild reaction conditions. The antibacterial activities of the synthesised products were examined which showed promising activities.