1489-22-1Relevant academic research and scientific papers
New method for the preparation of dibenzo[b,f][1,4]thiazepines
Fujii, Takayoshi,Hao, Wei,Yoshimura, Toshiaki
, p. 246 - 250 (2004)
The S-amination of 9H-thioxanthen-9-ol (2a) and 9-substituted derivatives 2b-e (Me (b), Et (c), iPr (d), Ph (e)) with O- mesitylenesulfonylhydroxylamine (MSH) was carried out. The expected product, 10-amino-9-hydroxy-9-isopropyl-9H-thioxanthenium mesitylenesulfonate (3d), was obtained in 78% yield from the corresponding thioxanthen-9-ol 2d. However, in the case of 2a-c and 2e the reaction led instead to dibenzo[b, f][1,4]thiazepines 6a-c and 6e in moderate yields.
