1489224-28-3Relevant articles and documents
Ranking relative hydrogen-bond strengths in hydroxybenzoic acids for crystal-engineering purposes
Aakeroey, Christer B.,Epa, Kanishka,Forbes, Safiyyah,Schultheiss, Nathan,Desper, John
, p. 14998 - 15003 (2013)
Systematic co-crystallizations resulting in a total of six new crystal structures involving either 3-hydroxy- or 4-hydroxybenzoic acid, complemented by calculated molecular electrostatic potential surfaces and existing structural data, have shown that in a competitive molecular recognition situation, the -OH moiety is a more effective hydrogen-bond donor than the -COOH moiety which, in turn, highlights that electrostatic charge can offer more useful guidance than acidity for predicting competitive hydrogen-bond preferences.