148975-71-7Relevant academic research and scientific papers
HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS
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, (2008/06/13)
Novel compounds useful as renin inhibitors are provided. The compounds are hydroxyazido derivatives having the structural formula STR1 wherein the substituents R 1 through R 7 are as defined herein. Analogs of these compounds which are ketozaido derivatives are also provided. Additionally disclosed re methods for using the novel compounds to treat hypertension, and pharmaceutical compositions containing the compounds. Of particular interest are formulations for oral administration.
