148982-08-5

Basic information

• Product Name: [4-(THIOPHENE-2-CARBONYL)-PHENYL]-THIOPHEN-2-YL-METHANONE
• Synonyms: [4-(THIOPHENE-2-CARBONYL)-PHENYL]-THIOPHEN-2-YL-METHANONE;1,4-DI-(2-THENOYL)BENZENE
• CAS NO: 148982-08-5
• Molecular Formula: C₁₆H₁₀O₂S₂
• Molecular Weight: 298.38
• Mol File: 148982-08-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4-(THIOPHENE-2-CARBONYL)-PHENYL]-THIOPHEN-2-YL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(THIOPHENE-2-CARBONYL)-PHENYL]-THIOPHEN-2-YL-METHANONE(148982-08-5)
• EPA Substance Registry System: [4-(THIOPHENE-2-CARBONYL)-PHENYL]-THIOPHEN-2-YL-METHANONE(148982-08-5)

Safety Data

• Hazardous Substances Data: 148982-08-5(Hazardous Substances Data)

Usage

General Description

[4-(thiophene-2-carbonyl)-phenyl]-thiophen-2-yl-methanone is a chemical compound with a complex structure that includes a combination of thiophene, carbonyl, phenyl, and methanone groups. It is primarily used in pharmaceutical and chemical research as a building block for synthesizing other compounds. This chemical is known for its potential biological activities and is being investigated for its potential use in drug discovery and development. Its unique structure and properties make it an important compound for studying the roles of thiophenes and carbonyl groups in various chemical and biological processes. Additional research may unlock new applications for this compound in the future.

Upstream product

• 6165-68-0 thiophene boronic acid 
• 100-20-9 terephthaloyl chloride 
• 188290-36-0 thiophene 

Downstream Products

• 1357562-87-8 1-{4-[1-(2-thienyl)-2,2-diphenylvinyl]phenyl}-1-(2-thienyl)-2,2-diphenylethene 

Relevant articles and documents

Synthesis and palladium(II) metal chemistry of thiazoline/imidazoline derived ligands: An efficient catalyst for cross-coupling reactions of arylboronic acids with acid chlorides and aryl halides

The synthesis, reactivity, spectroscopic characterization and catalytic activities of a series of Pd(II) complexes bearing the chelating ligands 2-(4,5-dihydrothiazol-2-yl)aniline (2) and 2-(4,5-dihydro-1H-imidazol-2-yl)aniline (3) are reported. The reactions of 2 with [Pd(COD)Cl2] in 1:1 and 1:2 (ligand into metal and metal into ligand) molar ratios afforded the mononuclear complexes, PdCl2{κ2?N,S ? 2?(4,5-dihydrothiazol-2-yl)aniline} (4), Pd{κ2?N,N’?2?(4,5-dihydrothiazol-2-yl)aniline}2 (5) and Pd{κ12?N,N’?κ22?N,S ? 2?(4,5-dihydrothiazol-2-yl)aniline}2 (6), respectively, in good yields. The neutral mononuclear palladium complexes PdCl2{κ2?N,N’?(4,5-dihydro-1H-imidazol-2-yl)aniline} (7) and Pd{κ2?N,N’?2?(4,5-dihydro-1H-imidazol-2-yl)aniline}2 (8) were synthesized using [Pd(COD)Cl2] with appropriate molar ratios. The palladium complexes 4–8 were evaluated for their catalytic activities in base assisted cross coupling reactions between acid chlorides and aryl halide with boronic acids. The complex 4 was found to be an efficient catalyst for producing unsymmetrical ketones (TOF = 19.8 min?1) while complex 7 was effective for making biaryls (TOF = 19.8 min?1).

Hetero-analogues of Hueckel Degenerate Systems and Related Compounds: Preparation of Thienyl-substituted Fulvalene and Electron-donating Tetrathiafluvalene Vinylogues and Conductive Complexes

1,4-Bisbenzene 9 has been prepared as a model of the six-fold Hueckel HOMO-degenerate tetracyclopentadienylideneethane biradical vinylogue.This extended dithienylfulvalene 9 was reduced reversibly to the dianion.Attempted prepara