149010-55-9

Upstream product

• 133719-55-8 ethyl 4-pyrimidin-5-yl)ethyl>-N-methylamino>benzoate 
• 10541-82-9 ethyl 4-(methylamino)benzoate 
• 165900-79-8 methyl 4-crotonate 
• 133719-37-6 methyl 4-butyrate 
• 133719-36-5 methyl 4--2-iodobutyrate 
• 133719-38-7 methyl 2-(dicyanomethyl)-4-butyrate 
• 165900-66-3 ethyl 4-pyrimidin-5-yl)ethyl>-N-methylamino>benzoate 

Downstream Products

• 133719-58-1 diethyl 4-pyrimidin-5-yl)ethyl>-N-methylamino>benzoyl-L-glutamate 

Relevant academic research and scientific papers

Synthesis and antitumor activity of pyrrolo[2,3-d]pyrimidine antifolates with a bridge chain containing a nitrogen atom

Novel pyrrolo[2,3-d]pyrimidine antifolates (1a, b and 2a, b) with a nitrogen atom in the bridge chain between the 2,4-diaminopyrrolo[2,3-d]pyrimidine and phenylene rings were designed and efficiently synthesized. These compounds exhibited more potent inhi