149010-58-2

Upstream product

• 136784-91-3 methyl 4-[2-(2-amino-4-hydroxythieno[2,3-d]pyrimidine-5-yl)ethyl]benzoate 
• 176208-31-4 4-<2-amino-4(3H)-oxopyrimidin-6-yl>thio-4-(4-carbomethoxyphenyl)-2-butanone 
• 149010-52-6 1-chloro-4-(4-carbomethoxyphenyl)-2-butanone 

Downstream Products

• 176208-39-2 dimethyl N-<4-<2-(2-amino-4(3H)-oxothieno<2,3-d>pyrimidin-5-yl)ethyl>benzoyl>-L-glutamate 

Relevant academic research and scientific papers

Synthesis of thieno[2,3-d]pyrimidine analogues of the potent antitumor agent N-{4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-YL)ethyl-benzoyl}-L- glutamic acid (LY231514)

Several thieno[2,3-d]pyrimidine analogues of the potent antitumor agent N-{4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-benzoyl}-L- glutamic acid (LY231514, 7) have been prepared by two different strategies. The first involved S-alkylati

Pyrrolopyrimidinyalglutaminate derivatives and their use

A condensed pyrimidine derivative of the formula (I): STR1 wherein the ring A stands for an optionally substituted 5-membered ring; B stands for an optionally substituted divalent 5- or 6-membered homo- or hetero-cyclic group; X stands for, among others,