149022-25-3 Usage
Description
((S)-(-)-2,2'-BIS(DIPHENYLPHOSPHIN)-1,1'-BINAPHTHALENE, also known as BINAP, is a chiral diphosphine ligand characterized by its unique binaphthalene backbone and phosphorus-containing substituents. ((S)-(-)-2 2'-BIS(DIPHENYLPHOSPHIN)-1 1& plays a crucial role in asymmetric catalysis, where it aids in the selective formation of carbon-carbon and carbon-heteroatom bonds. Its distinctive structure and properties have made it an indispensable reagent in various fields, including organic synthesis, pharmaceuticals, and material science.
Uses
Used in Asymmetric Catalysis:
BINAP is utilized as a chiral ligand in asymmetric catalysis for its ability to induce selectivity in chemical reactions, leading to the formation of enantioselective products. This is particularly important in the synthesis of pharmaceuticals and agrochemicals, where the desired biological activity is often associated with a specific enantiomer.
Used in Organic Synthesis:
In the field of organic synthesis, BINAP serves as a versatile ligand for the development of new synthetic methods and the improvement of existing ones. Its use in palladium-catalyzed cross-coupling reactions and other transition metal-catalyzed processes has significantly advanced the field, enabling the synthesis of complex organic molecules with high efficiency and selectivity.
Used in Pharmaceutical Industry:
BINAP plays a pivotal role in the pharmaceutical industry, where it is employed in the synthesis of biologically active compounds. Its ability to facilitate the formation of chiral centers with high enantioselectivity makes it a valuable tool for the production of enantiomerically pure drugs, which is essential for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Material Science:
In material science, BINAP has been applied in the development of new materials with unique properties. Its use in the synthesis of chiral polymers and other functional materials has contributed to the advancement of materials with potential applications in various fields, such as sensors, catalysts, and optoelectronics.
Check Digit Verification of cas no
The CAS Registry Mumber 149022-25-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,0,2 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 149022-25:
(8*1)+(7*4)+(6*9)+(5*0)+(4*2)+(3*2)+(2*2)+(1*5)=113
113 % 10 = 3
So 149022-25-3 is a valid CAS Registry Number.
