149035-16-5Relevant academic research and scientific papers
Chemoselective deprotection of trityl ethers using silica-supported sodium hydrogen sulfate
Das, Biswanath,Mahender, Gurram,Sunil Kumar, Vooturi,Chowdhury, Nikhil
, p. 6709 - 6711 (2004)
A highly selective method for the cleavage of trityl ethers over a wide range of functional groups has been developed using silica-supported sodium hydrogen sulfate (NaHSO4-SiO2) as a heterogeneous catalyst. The conversion occurred at room temperature and the yields of the alcohols were found to be excellent.
Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids
Ji, Peng,Zhang, Yueteng,Wei, Yongyi,Huang, He,Hu, Wenbo,Mariano, Patrick A.,Wang, Wei
, p. 3086 - 3092 (2019/05/01)
An approach for efficient synthesis of C-glycosyl amino acids is described. Different from typical photoredox-catalyzed reactions of imines, the new process follows a pathway in which α-imino esters serve as electrophiles in chemoselective addition reactions with nucleophilic glycosyl radicals. The process is highlighted by the mild nature of the reaction conditions, the highly stereoselectivity attending C-C bond formation, and its applicability to C-glycosylations using both armed and disarmed pentose and hexose derivatives.
Synthesis of simple adenosine diphosphate ribose analogues
Chevallier, Olivier P.,Migaud, Marie E.
, p. 1127 - 1143 (2008/12/23)
(Chemical Equation Presented) The synthesis of analogues of adenosine diphosphate ribose and acetylated adenosine diphosphate ribose, modified at the northern pentose, is reported. The stereochemistry at the acetylated centers was chosen to minimize acety
A facile and chemoselective cleavage of trityl ethers by indium tribromide
Yadav,Reddy, B.V. Subba,Srinivas,Maiti
, p. 528 - 529 (2007/10/03)
Trityl ethers are chemoselectively, deprotected to the corresponding alcohols in high yields by a catalytic amount of indium tribromide in aqueous acetonitrile. The method is compatible with various functional groups such as acetonides, acetates, benzoates, olefins, carbamates, esters and ethers present in the substrate.
A mild and selective cleavage of trityl ethers by CBr4-MeOH
Yadav, Jhillu S.,Subba Reddy, Basi V.
, p. 885 - 888 (2007/10/03)
Trityl ethers are selectively deprotected to the corresponding alcohols in high yields by CBr4 in refluxing methanol under neutral reaction conditions. Other hydroxyl protecting groups like isopropylidene, allyl, benzyl, acetyl, benzoyl, methyl
