149079-57-2Relevant academic research and scientific papers
SYNTHESIS OF BILE ACID - DRUG CONJUGATES: POTENTIAL DRUG - SHUTTLES FOR LIVER SPECIFIC TARGETING
Wess, G.,Kramer, W.,Schubert, G.,Enhsen, A.,Baringhaus, K.-H.,et al.
, p. 819 - 822 (2007/10/02)
Cholic acid (1) has been coupled via ω-aminoalkoxy spacer at C-3 to chlorambucil (3), HR 780 (4) and oxaproline peptide (5).Drug conjugates 9, 11, 18 exhibit strong affinity to specific bile acid transport systems.
