149109-10-4

Basic information

• Product Name: 7-Benzofurancarboxylic acid, 5-broMo-2,3-dihydro-, ethyl ester
• Synonyms: 7-Benzofurancarboxylic acid, 5-broMo-2,3-dihydro-, ethyl ester
• CAS NO: 149109-10-4
• Molecular Formula: C11H11BrO3
• Molecular Weight: 271.10724
• Mol File: 149109-10-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-Benzofurancarboxylic acid, 5-broMo-2,3-dihydro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Benzofurancarboxylic acid, 5-broMo-2,3-dihydro-, ethyl ester(149109-10-4)
• EPA Substance Registry System: 7-Benzofurancarboxylic acid, 5-broMo-2,3-dihydro-, ethyl ester(149109-10-4)

Safety Data

• Hazardous Substances Data: 149109-10-4(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 41177-72-4 5-bromo-2,3-dihydrobenzo[b]furan-7-carboxylic acid 

Downstream Products

• 1422205-96-6 5-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-2,3-dihydro-1-benzofuran-7-carboxylic acid 
• 1422205-95-5 ethyl 5-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-2,3-dihydro-1-benzofuran-7-carboxylate 
• 108551-59-3 7-carboxy-5-ethyl-2,3-dihydrobenzofuran 

Relevant articles and documents

HETEROCYCLIC DERIVATIVE AS MICROSOMAL PROSTAGLANDIN E SYNTHASE (mPGEs) INHIBITOR

The present invention provides a novel heterocyclic derivative or a pharmaceutically acceptable salt thereof. For example, the present invention provides a heterocyclic derivative of the general formula [1] or its tautomer, or a pharmaceutically acceptable salt thereof: wherein R 1 and R 2 are same or diferent aromatic ring, etc., and ring A is a heterocyclic ring. The compound of the invention or a pharmaceutically acceptable salt thereof has potent mPGES-1 inhibiting activity and is useful as an agent for the treatment or prevension of a disease, such as rheumatoid arthritis, osteoarthritis, temporomandibular joint disorders, low back pain, endometriosis, dysmenorrhea, overactive bladder, malignant tumors or neurodegenerative disease.