1491158-62-3 Usage
Description
Fmoc-Lys(Pal-Glu-OtBu)-OH is a complex organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals and chemicals. It is characterized by its ability to facilitate the formation of peptide bonds and is widely utilized in the development of new drugs and chemical compounds.
Uses
Fmoc-Lys(Pal-Glu-OtBu)-OH is used as an organic synthesis intermediate for the creation of various chemical compounds and pharmaceuticals. It is particularly valuable in the laboratory research and development process, as well as in the chemical production process, due to its role in peptide bond formation and its versatility in chemical reactions.
Used in Pharmaceutical Industry:
Fmoc-Lys(Pal-Glu-OtBu)-OH is used as a pharmaceutical intermediate for the development of new drugs. Its ability to facilitate peptide bond formation makes it an essential component in the synthesis of various therapeutic agents, contributing to the advancement of medical treatments and pharmaceutical innovations.
Used in Chemical Production:
In the chemical production industry, Fmoc-Lys(Pal-Glu-OtBu)-OH is employed as an intermediate in the synthesis of a wide range of chemical products. Its versatility and reactivity in chemical reactions make it a valuable asset in the development and manufacturing of various chemicals, driving innovation and progress in the industry.
Synthesis
In a flask aqueous sodium carbonate (1.8 g) was prepared followed by addition of THF
(800 mL) and then this mixture was cooled to 0-10 0C. To this mixture, (S)-2-((((9Hfluoren-9-yl)methoxy)carbonyl)amino)-6-aminohexanoic acid (4.59 g) was added.
Then, a solution of 1 -(tert-butyl) 5-(2,5-dioxopyrrolidin-1-yl) palmitoyl-L-glutamate
(corresponding to 5 g of 5-(tert-butoxy)-5-oxo-4-palmitamidopentanoic acid) prepared
according to example 2, was slowly added to above mixture at about 5 0C. The
reaction mixture was stirred for about 2 hours at 25 0C followed by addition of water
(600 mL). The solvents were subjected to distillation and then the pH of the obtained
compound is adjusted to 3.0 using 5N hydrochloric acid. The mixture was stirred for
1-2 hours and resulting solid was isolated filtration, washing with water (30 mL). The
obtained solid was dried under vacuum for 8 hours at about 45°C to afford title
compound in -85% yield.
Check Digit Verification of cas no
The CAS Registry Mumber 1491158-62-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,9,1,1,5 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1491158-62:
(9*1)+(8*4)+(7*9)+(6*1)+(5*1)+(4*5)+(3*8)+(2*6)+(1*2)=173
173 % 10 = 3
So 1491158-62-3 is a valid CAS Registry Number.