149140-60-3

Upstream product

• 149140-56-7 ethyl 5-chloro-2-hydroxy-3-(pyrrol-1-yl)benzoate 
• 149140-78-3 ethyl 3-aminio-5-chloro-2-hydroxybenzoate 
• 159323-96-3 ethyl 5-chloro-2-hydroxy-3-nitrobenzoate 
• 68-12-2 N,N-dimethyl-formamide 
• 149140-59-0 ethyl 2-acetoxy-5-chloro-3-(pyrrol-1-yl)benzoate 

Downstream Products

• 149140-62-5 ethyl 5-chloro-2-hydroxy-3-(2-hydroxymethylpyrrol-1-yl)benzoate 
• 149140-61-4 ethyl 5-chloro-3-(2-formylpyrrol-1-yl)-2-hydroxybenzoate 

Relevant academic research and scientific papers

New 5-HT3 (serotonin-3) receptor antagonists. V. Synthesis and structure-activity relationships of pyrrolo[2,1-c][1,4]benzoxazine-6-carboxamides.

This paper describes the discovery of structurally novel heterocyclic carboxamides which are highly potent 5-HT3 (serotonin-3) receptor antagonists. Pyrrolo[2,1-c][1,4]benzoxazine-6-carboxamides (12 and 20) were found to possess potent 5-HT3 receptor anta