149160-50-9Relevant articles and documents
The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph3PAu[SC(OR) = NPh] (R = Me, et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways
Yeo, Chien Ing,Ooi, Kah Kooi,Akim, Abdah Md,Ang, Kok Pian,Fairuz, Zainal Abidin,Halim, Siti Nadiah Binti Abdul,Ng, Seik Weng,Seng, Hoi-Ling,Tiekink, Edward R.T.
, p. 24 - 38 (2013/10/01)
The Ph3PAu[SC(OR) = NPh], R = Me (1), Et (2) and iPr (3), compounds are significantly cytotoxic to the HT-29 cancer cell line with 1 being the most active. Based on human apoptosis PCR-array analysis, caspase activities, DNA fragmentation, cell