149160-53-2Relevant academic research and scientific papers
The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph3PAu[SC(OR) = NPh] (R = Me, et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways
Yeo, Chien Ing,Ooi, Kah Kooi,Akim, Abdah Md,Ang, Kok Pian,Fairuz, Zainal Abidin,Halim, Siti Nadiah Binti Abdul,Ng, Seik Weng,Seng, Hoi-Ling,Tiekink, Edward R.T.
, p. 24 - 38 (2013/10/01)
The Ph3PAu[SC(OR) = NPh], R = Me (1), Et (2) and iPr (3), compounds are significantly cytotoxic to the HT-29 cancer cell line with 1 being the most active. Based on human apoptosis PCR-array analysis, caspase activities, DNA fragmentation, cell
Triorganophosphinegold(I) Carbonimidothioates
Hall, Veronica J.,Siasios, George,Tiekink, Edward R. T.
, p. 561 - 570 (2007/10/02)
The title compounds, R3PAuSC(=NPh)OR', R = Et, Ph or Cy and R' = Me, Et, Pr, Pri or Cy, have been prepared and characterized by spectroscopic methods (i.r., 1H and 13C n.m.r. and f.a.b. m.s.) and, in the case of the R = Ph and R'= Me compound,
