14918-68-4

Upstream product

• 108-31-6 maleic anhydride 
• 615-67-8 chloro-p-hydroquinone 

Downstream Products

• 14918-66-2 5,8-dihydroxy-2-methoxy-[1,4]naphthoquinone 
• 518-80-9 helminthosporin 
• 95393-73-0 1,4-dihydroxy-8-methoxy-6-methylanthraquinone 
• 81-53-8 2-chloro-1,4-dihydroxy-9,10-anthraquinone 
• 7475-11-8 1,4,6-trihydroxyanthracene-9,10-dione 
• 141111-35-5 3,5,8-Trihydroxy-1-methyl-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid benzyl ester 
• 2961-04-8 1,4,5-trihydroxy-9,10-anthracenedione 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 

Relevant academic research and scientific papers

Nouvelles methodes de synthese de la naphtopurpurine (trihydroxy-2,5,8 naphtoquinone-1,4)

The condensation of 1,2,4 trimethoxybenzene with maleic anhydride in the presence of AlCl3-NaCl affords, in a single step, naphtopurpurine 1, an important intermediate in the synthesis of naphtoquinone derived natural products.A different synthesis of compound 1 consists in the substitution of the halogen atom in 2-chloro or 2-bromo-naphthazirin by a methoxy group which is subsequently cleaved in an acidic medium or by a Lewis acid.