149184-11-2Relevant academic research and scientific papers
Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation
Hodge, Mathis,Chen, Qiao-Hong,Bane, Susan,Sharma, Shubhada,Loew, Maura,Banerjee, Abhijit,Alcaraz, Ana A.,Snyder, James P.,Kingston, David G.I.
supporting information; experimental part, p. 2884 - 2887 (2010/02/28)
A knowledge of the bioactive tubulin-binding conformation of paclitaxel (Taxol) is crucial to a full understanding of the bioactivity of this important anticancer drug, and potentially also to the design of simplified analogs. The bioactive con
