14919-38-1

Basic information

• Product Name: MYRISTOYL-DL-CARNITINE CHLORIDE
• Synonyms: MYRISTOYL-DL-CARNITINE CHLORIDE;(+/-)-MYRISTOYLCARNITINE CHLORIDE
• CAS NO: 14919-38-1
• Molecular Formula: C21H42ClNO4
• Molecular Weight: 408.02
• Product Categories: Lipid signaling
• Mol File: 14919-38-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: <10.2mg/ml in H2O
• CAS DataBase Reference: MYRISTOYL-DL-CARNITINE CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: MYRISTOYL-DL-CARNITINE CHLORIDE(14919-38-1)
• EPA Substance Registry System: MYRISTOYL-DL-CARNITINE CHLORIDE(14919-38-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37
• WGK Germany: 3
• Hazardous Substances Data: 14919-38-1(Hazardous Substances Data)

Usage

Description

MYRISTOYL-DL-CARNITINE CHLORIDE, also known as (+/-)-Myristoylcarnitine Chloride, is a homolog of Acetylcarnitine Chloride (A171990) and plays a significant role as an intermediate in lipid metabolism. It is a compound that contributes to the proper functioning of the body's energy production processes by facilitating the transport of fatty acids into the mitochondria for breakdown and energy generation.

Uses

Used in Pharmaceutical Industry:
MYRISTOYL-DL-CARNITINE CHLORIDE is used as an intermediate in lipid metabolism for its role in energy production. It aids in the transport of fatty acids into the mitochondria, where they are broken down to generate energy for the body's various functions.
Used in Research and Development:
In the field of research and development, MYRISTOYL-DL-CARNITINE CHLORIDE is used as a valuable compound for studying the intricacies of lipid metabolism and its impact on overall health. This understanding can lead to the development of novel therapeutic strategies and treatments for various metabolic disorders and conditions related to energy production.
Used in Sports Nutrition:
MYRISTOYL-DL-CARNITINE CHLORIDE may also be used in the sports nutrition industry as a supplement to support enhanced energy levels and improved physical performance. By promoting the efficient breakdown of fatty acids, it can potentially help athletes and active individuals maintain higher energy levels during intense workouts and competitions.

Biological Activity

(±)-myristoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-myristoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].