149194-61-6

Basic information

• Product Name: N-(1,3-BENZOTHIAZOL-2-YL)-2-HYDROXY-4-OXO-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOLE-3-CARBOXAMIDE
• Synonyms: AURORA KA-60;N-(1,3-BENZOTHIAZOL-2-YL)-2-HYDROXY-4-OXO-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOLE-3-CARBOXAMIDE
• CAS NO: 149194-61-6
• Molecular Formula: C18H10N4O3S2
• Molecular Weight: 394.43
• Mol File: 149194-61-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.74±0.1 g/cm3(Predicted)
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: N-(1,3-BENZOTHIAZOL-2-YL)-2-HYDROXY-4-OXO-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOLE-3-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-BENZOTHIAZOL-2-YL)-2-HYDROXY-4-OXO-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOLE-3-CARBOXAMIDE(149194-61-6)
• EPA Substance Registry System: N-(1,3-BENZOTHIAZOL-2-YL)-2-HYDROXY-4-OXO-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOLE-3-CARBOXAMIDE(149194-61-6)

Safety Data

• Hazardous Substances Data: 149194-61-6(Hazardous Substances Data)

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 1186-73-8 methanetricarboxylic acid trimethyl ester 
• 224313-89-7 methyl 2-hydroxy-4-oxo-4H-benzo<4,5>thiazolo<3,2-a>pyrimidine-3-carboxylate 

Relevant articles and documents

Methanetricarboxylates as key reagents for the simple preparation of heteroarylcarboxamides with potential biological activity. Part 2 [1]. Reaction of methanetricarboxylates with 2-aminopyridine, 2-aminopyrimidine, 2-aminothiazole and 2-aminobenzothiazole

The reaction of methanetricarboxylates 1a,b with 2-aminopyridine, 2- aminopyrimidine, 2-aminothiazole as well as 2-aminobenzothiazole yields corresponding heteroarylcarboxylic acid esters 2a,b, 5, 8, 11a,b. These heterocyclic esters were used as a starting material by the reaction with primary amines to obtaining a number of heteroarylcarboxylic amides 4a-j, 6, 10a,b, 13a-g bearing various substituents on the carboxamide group.