1492-02-0 Usage
Originator
Gludease,Kyowa Hakko,Japan,1972
Manufacturing Process
15.7 g of 2-amino-5-tert-butyl-1,3,4-thiadiazole (0.1 mol) and 17.6 g of
benzene sulfonyl chloride (0.1 mol) were dissolved in 150 ml dry pyridine and
heated over steam for 4 hr. The pyridine was removed by distillation under
reduced pressure and the residue treated with 50 ml 2N HCl. The solid
product, MP 162° to 163°C. was filtered off and recrystallized once from
benzene and twice from 50% aqueous EtOH.
Therapeutic Function
Oral hypoglycemic
Check Digit Verification of cas no
The CAS Registry Mumber 1492-02-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,9 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1492-02:
(6*1)+(5*4)+(4*9)+(3*2)+(2*0)+(1*2)=70
70 % 10 = 0
So 1492-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H15N3O2S2/c1-12(2,3)10-13-14-11(18-10)15-19(16,17)9-7-5-4-6-8-9/h4-8H,1-3H3,(H,14,15)
1492-02-0Relevant articles and documents
INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I
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Page 117, (2010/02/09)
The present invention relates to compounds with the formula (I) and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.
