14921-71-2

Basic information

• Product Name: 4-{[(E)-(4-ethoxyphenyl)methylidene]amino}benzoic acid
• CAS NO: 14921-71-2
• Molecular Formula: C₁₆H₁₅NO₃
• Molecular Weight: 269.2952
• Mol File: 14921-71-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 464.2°C at 760 mmHg
• Flash Point: 234.5°C
• Density: 1.13g/cm³
• Vapor Pressure: 2.05E-09mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 4-{[(E)-(4-ethoxyphenyl)methylidene]amino}benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(E)-(4-ethoxyphenyl)methylidene]amino}benzoic acid(14921-71-2)
• EPA Substance Registry System: 4-{[(E)-(4-ethoxyphenyl)methylidene]amino}benzoic acid(14921-71-2)

Safety Data

• Hazardous Substances Data: 14921-71-2(Hazardous Substances Data)

Upstream product

• 10031-82-0 4-ethoxybenzaldehyde 
• 150-13-0 4-amino-benzoic acid 
• 123-08-0 4-hydroxy-benzaldehyde 

Relevant articles and documents

The effect of position of tert-butyl tail group on the formation of liquid crystal in Schiff base ester based homologous series

We report a newly rod like calamatic liquid crystalline materials, which are constructed by the self-organization of a rod-like carboxylic acid derivative based on Schiff base ester as the linking group with tert butyl tail group. A newly series of 4-(tert-butyl) phenyl 4-((4-alkoxybenzylidene) amino) benzoate with different alkyl chain spacer (n = 1 to 8, 10, 12, 14, 16, and 18) were synthesized and their mesomorphic properties were investigated by differential scanning calorimetry and polarized optical microscopy. All homologous in present series displays mesophase in enantiotropically manner. Thermal stability of SmC-SmA is 137.5 °C. All the compounds were characterized by spectroscopic and elemental analysis. The effects of varying left alkyl side spacer on mesomorphism with its structurally related compounds in series have been discussed.

Synthesis of 3-acetoxyazetidin-2-ones and 3-hydroxyazetidin-2-ones with antifungal and antibacterial activity

The synthesis of a series of 3-acetoxyazetidin-2-ones 3a-n and 3-hydroxyazetidin-2-ones 6a-j is reported together with the antibacterial and antifungal evaluation of these compounds. An additional series of 3-acetoxyazetidin-2-ones 11a-h which possess a free carboxylic acid group on the N-1 aryl ring were obtained by treatment of suitably substituted Schiff bases 10a-h with acetoxyacetyl chloride. The novel bicyclic structures 7-acetoxy-6-phenyl-5-thia-1-azabicyclo[4.2.0]octan-8-one 13 and 7-hydroxy-6-phenyl-5-thia-1-azabicyclo[4.2.0]octan-8-one 14 were also obtained. Many of the compounds displayed antifungal activity in vitro when evaluated against the pathogenic fungi Cryptococcus neoformans, Candida albicans, Candida tropicalis, Candida parapsilosis, Candida glabrata, and Trichosporon cutaneum, while 3-acetoxyazetidin-2-ones 11a-h containing a free carboxylic acid group on the N-1 aryl ring displayed antibacterial activity against Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Bacillus subtilis, Klebsiella aerogenes and Escherischia coli.