149243-84-5Relevant academic research and scientific papers
CoI-Catalyzed Barbier Reactions of Aromatic Halides with Aromatic Aldehydes and Imines
Presset, Marc,Paul, Jér?me,Cherif, Ghania Nait,Ratnam, Nisanthan,Laloi, Nicolas,Léonel, Eric,Gosmini, Corinne,Le Gall, Erwan
supporting information, p. 4491 - 4495 (2019/02/27)
The reductive Barbier coupling of aromatic halides and electrophiles has been achieved using a CoBr2/1,10-phenanthroline catalytic system and over stoichiometric amounts of zinc. The reaction displayed a broad scope of substrates, including (hetero)aryl chlorides as pro-nucleophiles and aldehydes or imines as electrophiles, leading to diarylmethanols and diarylmethylamines in moderate to excellent yields, respectively.
Ni(COD)2/4-ClC6H4COR-catalyzed addition reactions of arylboroxines with aldehydes
Xing, Chun-Hui,Hu, Qiao-Sheng
supporting information; experimental part, p. 924 - 927 (2010/05/18)
Ni(COD)2/4-ClC6H4COR (R = H, CH3, Ph) was found to be an efficient catalyst system for the addition reactions of arylboroxines with aromatic and aliphatic aldehydes. The catalytically active species for Ni(COD)2/4-ClC6H4COR catalyst systems was likely to be their oxidative addition adducts, 4-RCOC6H4Ni(II)Cl(COD) complexes.
A new route to acyclic diaminocarbenes via lithium-halogen exchange
Snead, David R.,Ghiviriga, Ion,Abboud, Khalil A.,Hong, Sukwon
supporting information; experimental part, p. 3274 - 3277 (2009/12/01)
A lithium - halogen exchange route has been developed to generate acyclic diaminocarbenes (ADC) from chloroamidinium salts. Convenient access to various ADC complexes (B, Rh, lr, Pd) stems from a one-pot transmetalation protocol. Formation of a carbenoid species is suggested by 1D and 2D NMR studies with a 13C-labeled chloroamidinium precursor and also by X-ray structures of transition metal-carbene complexes. Rh-ADC complex 4 is an effective catalyst for the 1,2-addition of aryl boronic acids to aryl aldehydes.
Electroreductive coupling of organic halides with aldehydes catalyzed by nickel(0) complex with 2,2′-bipyridine
Budnikova,Keshner,Kargin
, p. 453 - 456 (2007/10/03)
A method of electrosynthesis of secondary alcohols from aldehydes and organic halides under the action of nickel(0) complexes is proposed. The key stage is addition of σ-complex RNi(I)bipy (bipy is 2,2′-bipyridine) to the aldehyde group.
A new synthesis of 3-isochromanone derivatives based on the reaction of o-acylbenzyllithiums with ethyl chloroformate
Kobayashi,Mannami,Kawakita,Tokimatsu,Konishi
, p. 582 - 585 (2007/10/02)
A new method for the preparation of 3-isochromanone derivatives is reported. The method consists of the ethoxycarbonylation of o-acylbenzyllithiums with ethyl chloroformate and the subsequent NaBH4 reduction of the resulting o-acylphenylacetic
