149281-19-6 Usage
Molecular Weight
429.56 g/mol
The relative molecular mass of Tetrahydrocurcumin is 429.56 grams per mole.
Structure
Tetrahydrocurcumin has a complex structure that includes a 1H-Indeno[5,4-f]quinoline core, a 7-carboxamide group, and an N-(1-cyano-1-methylethyl) side chain.
The 1H-Indeno[5,4-f]quinoline core is a tricyclic aromatic system with a fused pyridine ring.
The 7-carboxamide group is an amide derivative of a carboxylic acid located at the 7-position of the core structure.
The N-(1-cyano-1-methylethyl) side chain is a cyano-alkyl group attached to the nitrogen atom of the core structure.
Stereochemistry
(4aR,4bS,6aS,7S,9aS,9bS,11aR)
The stereochemistry of Tetrahydrocurcumin is defined by the configuration of its chiral centers (R and S) at specific positions in the molecule.
Derivative of Curcumin
Tetrahydrocurcumin is a derivative of curcumin, a naturally occurring bioactive compound found in turmeric.
This means that Tetrahydrocurcumin has a similar structure and properties to curcumin but with some modifications.
Antioxidant Properties
Tetrahydrocurcumin has the ability to neutralize free radicals and protect cells from oxidative damage.
This property makes it a potential candidate for the treatment of various diseases and conditions associated with oxidative stress.
Anti-inflammatory Properties
Tetrahydrocurcumin can help reduce inflammation in the body by inhibiting the production of pro-inflammatory molecules.
This property may be beneficial in the treatment of conditions such as arthritis and other inflammatory diseases.
Anti-cancer Properties
Tetrahydrocurcumin has been shown to exhibit anti-cancer properties by inhibiting the growth and proliferation of cancer cells.
This makes it a promising candidate for further research in cancer therapy.
Therapeutic Potential
Tetrahydrocurcumin has been studied for its potential therapeutic effects in conditions such as arthritis, diabetes, and cancer.
Its various properties, including antioxidant, anti-inflammatory, and anti-cancer activities, make it a valuable compound for pharmaceutical and medicinal research.
Application in Pharmaceutical and Organic Synthesis
Tetrahydrocurcumin is used in the fields of pharmaceuticals and organic synthesis due to its unique properties and potential therapeutic effects.
1H-Indeno[5,4-f]quinoline-7-carboxamide,N-(1-cyano-1-methylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)- can be used as a starting material for the synthesis of other related compounds or as an active ingredient in the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 149281-19-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,2,8 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 149281-19:
(8*1)+(7*4)+(6*9)+(5*2)+(4*8)+(3*1)+(2*1)+(1*9)=146
146 % 10 = 6
So 149281-19-6 is a valid CAS Registry Number.
149281-19-6Relevant academic research and scientific papers
17 BETA-SUBSTITUTED AZA-ANDROSTANE DERIVATIVES
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, (2008/06/13)
Compounds of the formula (I) wherein carbon atoms 1 and 2 are linked by a single bond or a double bond, R1 is hydrogen, methyl or ethyl, and A is a group of the formula -N(-R2)-X- wherein R2 is hydrogen or C1-C4 alkyl and X is C1-C1-2alkylene or C3 -C6cycloalkylidene; a group of the formula -N(-R2)-Y-Phe- wherein R2 is as defined above, Y is a direct bond or C1-C6-alkylene and Phe is an unsubstituted or substituted phenylene radical; a group of the formula -O-X- wherein X is as defined above, or a group -O-Y-Phe- wherein Y and Phe are as defined above, are inhibitors of 5alpha-reductase and can be used for the therapeutic treatment of the human and animal body
