1492906-11-2Relevant academic research and scientific papers
N-heterocyclic carbene-catalyzed domino hydroacylation/stetter reactions of salicyl alkynylphosphonates and aromatic aldehydes
Wang, Zhen-Qiang,Wang, Ying,Shi, De-Qing
, p. 88 - 97 (2013/09/12)
1,4-Dicarbonyl compounds 2 carrying a phosphonate group were obtained by utilizing a dually N-heterocyclic carbene (NHC) catalyzed domino reaction involving the intramolecular hydroacylation of salicyl alkynylphosphonates 1 and a subsequent intermolecular Stetter reaction with aromatic aldehyde at room temperature. In addition, 2 can also be applied for the synthesis of benzopyranopyrrole carrying a phosphonate group 4 in one pot and in moderate yield. ARKAT-USA, Inc.
