1492908-54-9Relevant academic research and scientific papers
Development of Axially Chiral Cyclo-Biaryldiol Ligands with Adjustable Dihedral Angles
Zhang, Pengxiang,Yu, Jipan,Peng, Fei,Wu, Xudong,Jie, Jiyang,Liu, Can,Tian, Hua,Yang, Haijun,Fu, Hua
supporting information, p. 17477 - 17484 (2016/11/23)
A new type of axially chiral cyclo-[1,1′-biphenyl]-2,2′-diol (CYCNOL) ligands with adjustable dihedral angles have been developed by varying the bridge chain length. Eight-, nine- and ten-membered cyclo-ligands were prepared and evaluated by using two representative examples: enantioselective additions of diethylzinc to aldehydes and organometallic reagents to enones. The results revealed that the fine regulation of dihedral angles through variation of the bridge chain length was effective in the asymmetric synthesis.
A convenient catalytic asymmetric conjugate addition reaction to enones using alkylzirconium reagents
Maksymowicz, Rebecca M.,Sidera, Mireia,Roth, Philippe M. C.,Fletcher, Stephen P.
supporting information, p. 2662 - 2668 (2013/10/21)
Alkylzirconium reagents undergo highly enantioselective copper-catalysed 1,4-addition reaction to cyclic enones. These reactions use alkylmetal species generated in situ from alkenes and the Schwartz reagent, and do not require premade organometallic reag
