149297-79-0

Basic information

• Product Name: Fludarabine Phosphate iMpurity B
• Synonyms: Fludarabine Phosphate iMpurity B;6-amino-7H-purin-2-ol;Fludarabine Phosphate EP Impurity B
• CAS NO: 149297-79-0
• Molecular Formula: C5H5N5O
• Molecular Weight: 151.1261
• Mol File: 149297-79-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 2.19±0.1 g/cm3(Predicted)
• PKA: 9.50±0.40(Predicted)
• CAS DataBase Reference: Fludarabine Phosphate iMpurity B(CAS DataBase Reference)
• NIST Chemistry Reference: Fludarabine Phosphate iMpurity B(149297-79-0)
• EPA Substance Registry System: Fludarabine Phosphate iMpurity B(149297-79-0)

Safety Data

• Hazardous Substances Data: 149297-79-0(Hazardous Substances Data)

Upstream product

• 10333-86-5 5-(N¹-benzoylthiocarbamoyl)aminoimidazole-4-carboxamide 
• 66224-66-6 adenine 

Relevant articles and documents

-

-

RING OPENING AND CLOSING REACTIONS OF IMIDAZOLES AND OTHER 1,3-DIAZAHETEROCYCLES WITH VINYL CHLOROFORMATE AND PHENYL CHLOROFORMATE

Treatment of imidazole and benzimidazole with vinyl chloroformate or phenyl chloroformate in weakly alkaline aqueous solution leads to their conversion into the corresponding imidazol-2-ones; in weakly acidic solutions these chloroformates convert adenine into isoquanine, 6-methylaminopurine into 1-methylisoquanine and pyrimidine into an acyclic product.