1493-03-4

Basic information

• Product Name: DIFLUOROIODOMETHANE
• Synonyms: DIFLUOROIODOMETHANE;IODODIFLUOROMETHANE;Difluoroiodomethane 95%;Difluoroiodomethane95%;Difluoromethyl iodide;Difluoro(iodo)methane97%
• CAS NO: 1493-03-4
• Molecular Formula: CHF₂I
• Molecular Weight: 177.92
• Mol File: 1493-03-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: -122 °C
• Boiling Point: 21.6 °C
• Appearance: /
• Density: 3.2380
• Vapor Pressure: 841mmHg at 25°C
• Refractive Index: 1.443
• CAS DataBase Reference: DIFLUOROIODOMETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: DIFLUOROIODOMETHANE(1493-03-4)
• EPA Substance Registry System: DIFLUOROIODOMETHANE(1493-03-4)

Safety Data

• Hazard Codes: Xi
• Statements: 20
• Safety Statements: 23-36/37/39
• RIDADR: 3163
• HazardClass: IRRITANT
• Hazardous Substances Data: 1493-03-4(Hazardous Substances Data)

Usage

General Description

Difluoroiodomethane is a chemical compound with the formula CF2I and is also known as fluorodifluoromethyl iodide. It is a colorless, volatile liquid that is used as a reagent in organic synthesis and as a refrigerant in some industrial applications. Difluoroiodomethane is a halomethane, which means it contains a carbon atom bonded to two fluorine atoms and one iodine atom. It is considered to be a relatively stable compound, but it is also a potent greenhouse gas with a high global warming potential. Due to its potential impact on the environment, there is ongoing research into finding more environmentally friendly alternatives for its various applications.

InChI:InChI=1/CHF2I/c2-1(3)4/h1H

Upstream product

• 75-47-8 iodoform 
• 76-04-0 2-chloro-2,2-difluoroacetic acid 
• 87189-16-0 potassium 2-bromo-2,2-difluoroacetate 
• 58201-66-4 (bromodifluormethyl)triphenylphosphonium bromide 
• 19740-21-7 Kalium-chlordifluoracetat 
• 354-08-5 bromodifluoroacetic acid 
• 1511-62-2 bromodifluoromethane 
• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 677-67-8 fluorosulfonyldifluoroacetyl fluoride 
• 1717-59-5 2,2-difluoro-2-(fluorosulfonyl)acetic acid 
• 1512-30-7 difluoromethylsulfonyl chloride 
• 335-06-8 trifluoromethyltrimethylsilane 
• 2314-97-8 iodotrifluoromethane 
• 7553-56-2 iodine 

Downstream Products

• 75-10-5 Difluoromethane 
• 1577210-89-9 (3-(difluoromethoxy)propyl) benzene 

Relevant articles and documents

THE HYDROLYSIS OF BROMODIFLUOROMETHYLTRIPHENYLPHOSPHONIUM BROMIDE

Hydrolysis of +Br- afforded a high yield of bromodifluoromethane and triphenylphosphine oxide.Hydrolysis in the presence of a radioactive isotope of bromine or sodium iodide gave unequivocal evidence that the mechanism for this reaction proceeds through a difluorocarbene intermediate.

BCL-2 PROTEIN INHIBITORS

Various Bcl-2 protein inhibitors are described, along with methods of using them to treat conditions characterized by excessive cellular proliferation, such as cancer and tumors. In various embodiments the Bcl-2 protein inhibitors are compounds or pharmaceutically acceptable salts of the following Formula (I), where the variables in Formula (I) are defined herein.

Production method of fluoroalkyl iodide

The invention discloses a production method of a fluoroalkyl iodide, and particularly discloses a production method of a fluoroalkyl iodide as shown in a formula (I) as shown in the specification. Theproduction method of the fluoroalkyl iodide as shown in the formula (I) as shown in the specification comprises the following step: in a first solvent, subjecting a compound as shown in a formula (II) as shown in the specification and an iodide to an iodination reaction as shown in the specification. The raw materials used in the method are easy to obtain, and prices are low; and the method is high in conversion rate and yield, and the tolerability to functional groups is high.