149323-68-2

Basic information

• Product Name: 4-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID
• Synonyms: 4-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID;4-(2-FORMYL-1H-PYRROL-1-YL)BENZOIC ACID
• CAS NO: 149323-68-2
• Molecular Formula: C₁₂H₉NO₃
• Molecular Weight: 215.2
• Product Categories: pharmacetical
• Mol File: 149323-68-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 425.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.25±0.1 g/cm3(Predicted)
• PKA: 3.77±0.10(Predicted)
• CAS DataBase Reference: 4-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID(149323-68-2)
• EPA Substance Registry System: 4-(2-FORMYL-PYRROL-1-YL)-BENZOIC ACID(149323-68-2)

Safety Data

• Hazardous Substances Data: 149323-68-2(Hazardous Substances Data)

Usage

Description

4-(2-Formyl-pyrrol-1-yl)-benzoic acid is a chemical compound characterized by the molecular formula C13H9NO3. It is a derivative of benzoic acid, featuring a formyl group and a pyrrole ring, which endows it with unique chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
4-(2-Formyl-pyrrol-1-yl)-benzoic acid is used as a key intermediate in the synthesis of new drugs, particularly for the development of pharmaceuticals with novel therapeutic properties. Its unique chemical structure allows for the creation of diverse drug candidates that can target specific biological pathways or receptors.
Used in Organic Synthesis:
In the field of organic synthesis, 4-(2-Formyl-pyrrol-1-yl)-benzoic acid serves as a valuable building block for the construction of complex organic molecules. Its reactivity and functional groups make it suitable for various synthetic transformations, enabling the preparation of a wide range of organic compounds.
Used in Chemical Research:
4-(2-Formyl-pyrrol-1-yl)-benzoic acid is utilized in chemical research to explore its properties, reactivity, and potential applications. Researchers can use this compound to study its interactions with other molecules, its behavior under different conditions, and its potential as a precursor for the synthesis of other valuable compounds.

Upstream product

• 149323-67-1 Methyl 4-(2-formylpyrrol-1-yl)benzoate 

Relevant articles and documents

FUSED HETEROCYCLIC COMPOUNDS, HAVING ANGIOTENSIN II ANTAGONISTIC ACTIVITY

Fused heterocyclic compounds of the formula (I): STR1 wherein R. sup.1 is an optionally substituted hydrocarbon residue which may be attached through a hetero atom; R 2 is a group capable of forming an anion or a group convertible thereinto; R 3 is an optionally substituted aromatic hydrocarbon or heterocyclic residue which contains at least one hetero atom; X is a direct bond or a spacer having an atomic length of two or less between the R 3 group and the ring W group; W is an optionally substituted aromatic hydrocarbon or heterocyclic residue which contains at least one hereto atom; a,c and d are independently selected from the group consisting of one or two optionally substituted carbon atoms and one or two optionally substituted hetero atoms; b and e are independently selected from the group consisting of one optionally substituted carbon atom and one optionally substituted nitrogen atom wherein one of b or e must be nitrogen; the dotted line is a bond to form one double bond; n is an integer of 1 or 2 and when a, which is an optionally substituted carbon atom, is taken together with R 1, the following group: STR2 may form a ring group; provided that when STR3 is a benzimidazole, thieno[3,4-d] imidazole, or thieno[2,3-d] imidazole ring, at least one of the group: STR4 and R 3 is an optionally substituted heterocyclic residue; and the pharmaceutically acceptable salts thereof, have potent angiotensin II antagonistic activity and antihypertensive activity, thus being useful as therapeutic agents for treating circulatory system diseases such as hypertensive diseases, heart diseases (e.g. hypercardia, heart failure, cardiac infarction, etc.), strokes, cerebral apoplexy, nephritis, etc.