149366-79-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Boc-aminomethylpyrrolidine is used as a pharmaceutical intermediate for the synthesis of various medications, contributing to the development of new therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-Boc-aminomethylpyrrolidine is utilized as a building block for the production of biologically active compounds, facilitating the creation of innovative pharmaceuticals with potential health benefits.
Used in Drug Discovery and Development:
3-Boc-aminomethylpyrrolidine is employed in drug discovery and development processes, where its potential role in creating new drugs is being explored, highlighting its importance in advancing pharmaceutical research.

InChI:InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)12-7-8-4-5-11-6-8/h8,11H,4-7H2,1-3H3,(H,12,13)

Upstream product

• 155497-10-2 (1-benzyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester 
• 172477-98-4 1-benzyl-3-<(t-butyloxycarbonyl)methylamino>-pyrrolidine 

Downstream Products

• 582325-52-8 (1-benzoyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester 
• 802983-63-7 1-(3,3-diphenyl-propionyl)-pyrrolidin-3-ylmethyl carbamic acid tert-butyl ester 
• 802983-61-5 N-[1-benzhydryl]-3-aminomethyl-3-tert-butoxycarbonylpyrrolidine 
• 802983-59-1 {1-[6,6-bis-(4-fluoro-phenyl)-hexanoyl]-pyrrolidin-3-ylmethyl}-carbamic acid tert-butyl ester 
• 802983-60-4 1-(3-aminomethyl-pyrrolidin-1-yl)-6,6-bis-4-fluoro-phenyl-hexan-1-one 

Relevant academic research and scientific papers

Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors

We previously reported the small organic N-type calcium channel blocker NP078585 that while efficacious in animal models for pain, exhibited modest L-type calcium channel selectivity and substantial off-target inhibition against the hERG potassium channel

NAPHTHALENE CARBOXAMIDES AND THEIR DERIVATIVES USEFUL AS NEW ANTI-ANGIOGENIC AGENTS

The invention relates to compounds represented by Formula (I) and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein each of R1a-d , R2a-b , R3, and X1 are defined herein, The invention also relates to pharmaceutical compositions containing the compounds of Formula (I) and to methods of treating hyperproliferative disorders in a mammal by administering compounds of Formula(l).

3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS

The invention relates to compounds that are derivatives of 3-aminomethyl-pyrrolidine of the formulas: wherein: Y is (X2)1A or (X1)mCR4A2; W is CR4 or N; R1-R4 are noninterfering substituents; n is 0-7; 1 and m are independently 0 or 1; X1-X2 are linkers;

Indole, azaindole and related heterocyclic pyrrolidine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with amido piperazine derivatives. These compounds possess unique antiviral activity

BENZOFUSED HETEROARYL AMIDE DERIVATIVES OF THIENOPYRIDINES USEFUL AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND METHODS FOR THEIR USE

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

Pyrrolidine derivatives-CCR-3 receptor antagonists

This invention relates to certain 3-aminomethylpyrrolidine derivatives of Formula (I): that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.