149376-69-2Relevant academic research and scientific papers
Synthesis of Peptide Nucleic Acid Monomers Containing the Four Natural Nucleobases: Thymine, Cytosine, Adenine, and Guanine and Their Oligomerization
Dueholm, Kim L.,Egholm, Michael,Behrens, Carsten,Christensen, Leif,Hansen, Henrik F.,et al.
, p. 5767 - 5773 (2007/10/02)
The preparation of mixed-sequence PNAs (PNAs containing the four natural nucleobases; thymine, cytosine, adenine, and guanine) is described.The PNA monomers containing thymine, Cbz-protected cytosine, or adenine or benzyl-protected guanine were prepared v
Peptide Nucleic Acids containing Adenine or Guanine recognize Thymine and Cytosine in Complementary DNA Sequences
Egholm, Michael,Behrens, Carsten,Christensen, Leif,Berg, Rolf H.,Nielsen, Peter E.,Buchardt, Ole
, p. 800 - 801 (2007/10/02)
Peptide nucleic acid (PNA) monomer building blocks for the introduction of G and A are prepared and used to synthesise H-T4XT5-Lys-NH2 (X=G or A), which are shown by Tm measurements to recognize their complementary DNA sequences in both the parallel (N-te
